Excitation-contraction coupling and the ultrastructure of smooth muscle.
نویسندگان
چکیده
منابع مشابه
Excitation-contraction coupling in airway smooth muscle.
Excitation-contraction (EC) coupling in striated muscles is mediated by the cardiac or skeletal muscle isoform of voltage-dependent L-type Ca(2+) channel (Ca(v)1.2 and Ca(v)1.1, respectively) that senses a depolarization of the cell membrane, and in response, activates its corresponding isoform of intracellular Ca(2+) release channel/ryanodine receptor (RyR) to release stored Ca(2+), thereby in...
متن کاملExcitation-contraction coupling in vertebrate smooth muscle: correlation of ultrastructure with function.
page Important Notice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . i Editor’s Page l . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . ii APS Membership Status . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 The American Physiological Society . . . . . ..‘.....................
متن کاملTemporal aspects of excitation-contraction coupling in airway smooth muscle.
In airway smooth muscle (ASM), ACh induces propagating intracellular Ca2+ concentration ([Ca2+]i) oscillations (5-30 Hz). We hypothesized that, in ASM, coupling of elevations and reductions in [Ca2+]i to force generation and relaxation (excitation-contraction coupling) is slower than ACh-induced [Ca2+]i oscillations, leading to stable force generation. When we used real-time confocal imaging, t...
متن کاملThe Ultrastructure of Frog Ventricular Cardiac Muscle and Its Relationship to Mechanisms of Excitation-contraction Coupling
Frog ventricular cardiac muscle has structural features which set it apart from frog and mammalian skeletal muscle and mammalian cardiac muscle. In describing these differences, our attention focused chiefly on the distribution of cellular membranes. Abundant inter cellular clefts, the absence of tranverse tubules, and the paucity of sarcotubules, together with exceedingly small cell diameters ...
متن کاملExcitation-contraction coupling in denervated muscle
Skeletal muscle atrophy can be defined as a wasting or decrease in muscle mass and muscle force generation owing lack of use, ageing, injury or disease. Thus, the etiology of atrophy can be different. Atrophy in denervated muscle is a consequence of two factors: 1) the complete lack of motoneuron activity inducing the deficiency of neurotransmitter release and 2) the muscles disuse. The balance...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1985
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.57.4.497